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br Disclosures br Acknowledgments This study
2019-04-24
Disclosures Acknowledgments This study was supported by the Austrian National Science Fund (FWF), Grant # SFB-F4704. Introduction Acute lymphoblastic leukemia (ALL) is the most frequent childhood malignancy. Extramedullary involvement of the kidneys is seen in around 7% when assessed by in
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In summary current evidence suggests that
2019-04-23
In summary, current evidence suggests that bone-targeted agents reduce morbidity from metastatic disease to bone, and potentially improve quality of life in patients with metastatic breast cancer. As there are costs and potential adverse effects associated with these agents, care should be taken in
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The investigators suggest use of
2019-04-23
The investigators suggest use of doxycycline, which is effective for both diseases, as a possible empirical treatment at the primary level of care. Because the consequences of an untreated true case of rickettsiosis or leptospirosis are much greater than are those of unnecessary treatment, Mayxay an
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La pol tica institucionalizada se
2019-04-23
La política institucionalizada se convirtió y se aceptó, por parte de los actores relevantes del sistema (neo-oligarquías e instituciones), y en gran medida por lo benevolente y bondadosa que sería para los intereses del gran capital, como el vehículo hacia el futuro del Estado. Se decretó que la cr
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br Environmental pollution is a global problem and the subje
2019-04-23
Environmental pollution is a global problem and the subject of increasing worldwide public health concern. In particular, air pollution is regarded as the largest single environmental risk to health. More than 80% of people living in urban areas that monitor air pollution are exposed to air qualit
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In the days before Christmas adverse
2019-04-23
In the days before Christmas, 1952, adverse weather conditions and the burning of sulphurous coal led to the death of almost 12 000 people in London. Despite improvements in pollution prevention since the “Great Smog”, London continues to experience toxic air pollution linked to thousands of prematu
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What lies ahead Clearly the extremely ambitious
2019-04-23
What lies ahead? Clearly the extremely ambitious goals and targets set by the UNCoLSC have not been reached, and challenges must be overcome. While the current evaluation highlights several challenges and strategies for action, a clear process in moving forward would be to link this bottleneck analy
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Despite impressive progress towards elimination social unres
2019-04-23
Despite impressive progress towards elimination, social unrest, gaps in the coverage of populations at risk, competing health interests, and possible donor fatigue present challenges to successful elimination of human African trypanosomiasis caused by and subsequent maintenance of this status. The t
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br Community based bundled health interventions are complex
2019-04-23
Community-based bundled health interventions are complex and challenging to implement, monitor, and assess in informal settlements (slums). Such settlements in urban areas are generally characterised by congestion, squalid conditions, deprivation, violence, crime, and poor sanitation. In Asia and
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br Panels A to D show intracardiac recordings of the
2019-04-22
Panels A to D show intracardiac recordings of the HRA extrastimuli with A1A2 intervals of 320−290ms at a basic CL of 600ms. The AV conduction intervals were increased gradually rather than suddenly, so that an Ae with an A2–V2–Ae sequence could be provoked only at 310ms and 300ms, followed by no A
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LQTS is classified into subtypes LQT to LQT based
2019-04-22
LQTS is classified into subtypes LQT1 to LQT13 based on the site of genetic mutation. Each type possesses distinct clinical characteristics and a different prognosis. Treatment choice depends partly on individual phenotype and partly on genotype. Among Asian countries, several reports have been publ
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M s all de la tiran a de
2019-04-22
Más allá de la tiranía de las vanidades, existían sólidos argumentos que justificaban el alejamiento de Paz con respecto carnosic acid la poesía y la persona de Neruda. Con leve antelación a sus contemporáneos chilenos, Octavio Paz resaltaba dos principales defectos en la producción poética de Nerud
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Climate change will have far reaching effects
2019-04-22
Climate change will have far-reaching effects on how we build, organise, and manage health systems as complex institutions. Yet, to date, these challenges have largely been ignored by the research community. Despite substantial work by WHO on the interface between climate and health, two major conf
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br Planteamientos Previos El presente estudio
2019-04-22
Planteamientos Previos El presente estudio muestra la estrecha relación entre los procesos identitarios y las transformaciones de los contextos migratorios. Centrándose en el caso de los migrantes indígenas de Otavalo (Ecuador) en una de las ciudades del sur de España, la investigación parte de u
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Agosto toma la medida del relato hist
2019-04-22
Agosto toma la medida del relato histórico en algunas ocasiones, de la crónica periodística en otras, para obtener una narración que ha llegado a entremezclarse con la realidad, o al menos con una investigación académica bien documentada, al grado tal que es bastante común encontrarla citada en artí
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