• br Materials and methods br Results

  2021-05-05

  

  Materials and methods Results As shown in Table 1, blood urea nitrogen and serum creatinine levels were significantly elevated at both 1st and 7th days of pyelonephritis, when compared with those of the control group (PBetamethasone formation or intratubular neutrophils, while tubules showed

• It is well known that the tumor suppressor p plays

  2021-05-05

  

  It is well known that the tumor suppressor p53 plays an important role in regulating the GW441756 receptor and cellular senescence [43,46,48]. For example, FOXO4 could interact with P53, which selectively induced apoptosis in senescent cells [48]. In addition, loss of MECP2 was found to lead to the

• Introduction Ewing sarcomas primitive neuroectodermal tumors

  2021-05-05

  

  Introduction Ewing sarcomas/primitive neuroectodermal tumors (ES/PNETs) are relatively infrequent but the second most common sarcoma of the bone next to osteosarcoma. Nearly 80% of them occur in persons younger than 20years. Most of them arise from the bone, but 10 to 20% of them from soft tissue.

• In an effort to discover additional GPCRs directing the migr

  2021-05-05

  

  In an effort to discover additional GPCRs directing the migratory events of responding B cells, we identified Epstein-Barr virus (EBV)-induced gene 2 (EBI2) as a promising candidate. The gene encoding EBI2 (Ebi2, also known as Gpr183) was originally identified together with Ebi1 (Ccr7) as the most h

• br Materials and methods br Results br Discussion Innate imm

  2021-05-05

  

  Materials and methods Results Discussion Innate immunity plays an essential role in the control and elimination of bacterial infection through production of inflammatory cytokines (Liu et al., 2015). Production of inflammatory cytokines requires the recognition of bacterial pathogen-associa

• Introduction Ubiquitylation is a post translational modifica

  2021-05-05

  

  Introduction Ubiquitylation is a post-translational modification which impacts almost every biological process in the cell. Dysregulation of the ubiquitylation pathway is associated with several diseases, including cancer, neurodegenerative disorders, and immunological dysfunctions. Single ubiquiti

• To ascertain separation of the distinct enzymatic activities

  2021-05-05

  

  To ascertain separation of the distinct enzymatic activities found in this protein preparation following separation on the HAP column, a rigorous quantitative analysis was conducted on the nickel–agarose elution and HAP FT pools of protein. For these analyses, each pool of protein was dialyzed in th

• br Synthesis and mechanism of

  2021-05-05

  

  Synthesis and mechanism of fluorescent DNA-CuNMs Application of fluorescent DNA-CuNMs Summary and conclusions In summary, we introduce recent research progress in the synthesis and various applications of DNA-CuNMs. DNA-CuNMs with novel catalytic, electrical and optical properties can be ob

• DSBs can be repaired by two major

  2021-05-05

  

  DSBs can be repaired by two major pathways: canonical non-homologous end-joining (c-NHEJ) and homologous recombination (HR) (Chapman et al., 2012). c-NHEJ comprises two sub-pathways, a resection-independent process and a resection-dependent process, and can rejoin break ends with little or no sequen

• Structural homology modelling Intensive Phyre modelling was

  2021-05-05

  

  Structural homology modelling. Intensive Phyre2 modelling [44] was performed using the primary amino Cerulenin sequence of A1S_0222 as input to generate an atomistic 3D-homology model of A1S_0222. The fit to the SAXS data of the homology model as well as the fit to the data of the E. coli adenine-N

• br STAR Methods br Acknowledgments We

  2021-05-05

  

  STAR★Methods Acknowledgments We are grateful to Matthias Mayer at ZMBH in Heidelberg for access to his CD-spectrometer and his help in data interpretation. Technical support by Wolfgang Weinig is gratefully acknowledged. This project was financially supported by the European Union as part of t

• Collectively the results presented here provide new insights

  2021-05-05

  

  Collectively, the results presented here provide new insights into ligand binding, clustering, spatial distribution, and phosphorylation of DDR1b and DDR2 in response to soluble collagen I. As depicted in the cartoon of Scheme 1, we postulate a model in which the spatial distribution and assembly of

• VKGILS-NH2 br Conflicts of interest br Acknowledgements br

  2021-05-05

  

  Conflicts of interest Acknowledgements Lung cancer continues to be the leading cause of cancer deaths in the US and worldwide., Non–small-cell lung cancer (NSCLC) remains the predominant form of lung cancer (approximately 85%)., With some improvements in surgical techniques and combined ther

• Emi protein consists of an N

  2021-04-30

  

  Emi2 protein consists of an N-terminal regulatory region and a C-terminal functional region. The C-terminal region contains a destruction box (D-box), which likely competes with APC/C substrates (including cyclin B) for APC/C binding, and a zinc-binding region (ZBR), which somehow inhibits APC/C ubi

• In countries such as China where there is

  2021-04-30

  

  In countries such as China where there is a high commercial production of rice, the use of rice husk ash (RHA) as an alternative cementing material can become a great asset for environmental rehabilitation and address the difficult disposal issues associated with this agricultural waste [23]. RHA po

16445 records 684/1097 page Previous Next First page 上5页 681682683684685 下5页 Last page