• br Conclusions br Declaration of interest br Acknowledgment

  2021-01-25

  

  Conclusions Declaration of interest Acknowledgment This work was supported by an AIRC (Associazione Italiana Ricerca Cancro-Milan) Grant KFR062-2 to A.G.L, by Ricerca Funds by Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico (Grant No. 180/01) and by the ERA-NET “ERare” (Grant GO

• The action of pt PGE as an EP receptor

  2021-01-25

  

  The action of 17-pt-PGE2 as an EP1 receptor agonist [34] was demonstrated in several experimental settings, including cancer, neurons, vascular system, kidney and was confirmed by application of EP1 receptor selective antagonists [35], [36], [37], [38], [39], [40], [41]. Receptor binding studies in

• br Acknowledgments The research in this study was supported

  2021-01-25

  

  Acknowledgments The research in this study was supported by grants from CMHS, UAE University and Qatar University. The authors gratefully acknowledge Dr. R Lukas (Barrow Neurological Institute, Phoenix, AZ, USA) for SH-EP1 lrrk2 stably expressing the human α7 nACh and human α4β2 nACh receptor an

• br Chondroitin sulfate proteoglycans CSPGs are major compone

  2021-01-25

  

  Chondroitin sulfate proteoglycans (CSPGs) are major components of the extracellular matrix in cartilage. Each CSPG comprises a single core protein and attached chondroitin sulfate (CS), belonging to the glycosaminoglycan family of sugar chains. CSPGs and CS are involved in numerous biological and

• br Acknowledgements This study was

  2021-01-25

  

  Acknowledgements This study was financially supported by the National Special Research Programs for Non-Profit Trades (Agriculture) (Grant No. 201303045) and the Basic Foundation for Scientific Research of the State-level Public Welfare Institutes of China (Grant No. 2013JB10). Introduction L

• Recently a method for in vivo photoactivation

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  Recently, a method for in vivo photoactivation of indocid expressing PA-GFP in precise microanatomical compartments was described (Victora et al., 2010), which makes it possible to optically mark Tfh cells and track them 20 hr later (Shulman et al., 2013). Unexpectedly, it was reported that Tfh cel

• br Future perspectives Understanding how peptides

  2021-01-25

  

  Future perspectives Understanding how peptides are degraded, particularly those which may be therapeutically useful, such as GLP-1, has proved to be invaluable in providing a rationale for the development of a novel class of therapeutic agents. However, while DPP-4 plays an important role in the

• GSK180 The data from the Sur

  2021-01-25

  

  The data from the Sur lab have showed DNA-PK is involved in metabolic gene regulation in response to insulin. DNA-PK regulates fatty GSK180 synthesis by modulating the protein expression of fatty acid synthase (FAS) in a feeding-dependent manner. DNA-PK induces the activation of Upstream Stimulatory

• Experimental studies offer a means of developing an

  2021-01-25

  

  Experimental studies offer a means of developing an empirical basis for the development of forensic protocols in the investigations of specific crime types [12]. Such an evidence nsc library australia for ICST cases will help enable the identification of situations when there is likely to be recove

• Expression of MGMT in human cells can be switched off

  2021-01-23

  

  Expression of MGMT in human 20187 can be switched off by enzymatic methylation of a cytosine residue in the MGMT promoter sequence. In this regard, both MGMT and the mismatch repair function MLH1 belong to a subset of DNA repair genes that are subjected to epigenetic control. In consequence, about

• The first purpose of the current study was to

  2021-01-23

  

  The first purpose of the current study was to characterize a standardized experimental model of postprandial hyperlipidemia in various rodent species. To our knowledge this study provides the most comprehensive and systematic evaluation of rodent models of postprandial hyperlipidemia to date. We ada

• As shown in Figs a and b

  2021-01-23

  

  As shown in Figs. 3(a) and (b), with the SO effect, the absolute values of the VDEs change by at most 0.19eV. Table 1 also shows that the observed peak splitting energies in the Sm-Ho complexes were reproduced even without the SO effect. Considering its significant importance in the electronic struc

• A comparison between tinnitus and controls subjects

  2021-01-23

  

  A comparison between tinnitus and controls subjects showed increased activity in the left AUD and PHC for the gamma frequency band. The link between gamma band activity in the AUD and tinnitus has been identified using both EEG (van der Loo et al., 2009) and MEG (Weisz et al., 2005, 2007). This is

• br Progestogens and venous thromboembolism clinical data br

  2021-01-23

  

  Progestogens and venous thromboembolism: clinical data Progestogens and haemostatis: biological studies For many years, the effect of HT on haemostatis has been largely investigated in observational studies as well as in high evidence level studies among users of oral and transdermal estrogens

• The need for dedicated DAPT updates is well justified by

  2021-01-23

  

  The need for dedicated DAPT updates is well justified by the large amount of data and new information generated in the field over the past few years. As expected, the ACC/AHA and ESC updates contain large areas of overlap as well as some differences. Differences were largely explained by the differe

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