• GLPG0634 Discussion It is widely known that wild type p prot

  2018-11-01

  

  Discussion It is widely known that wild-type p53 protein is a tumor suppressor, whereas mutant p53 proteins can actively contribute to tumorigenesis. p53 mutations have been revealed to be present in numerous human tumors (Muller and Vousden, 2013). Recently, Freed-Pastor et al. reported the signif

• The influence of gap distance on production

  2018-11-01

  

  The influence of gap distance on production rate of electrospun fiber availability also investigated by the one-way ANOVA analysis to provide statistical validation on observation results. The production rates of 15.2, 25.4, and 35.6cm gap distance are used as response variables in the test for sign

• We conducted two additional exploratory analyses First

  2018-11-01

  

  We conducted two additional exploratory analyses. First, following up a recent examination of the developmental trajectories of the EEG from children in the BEIP study (Stamoulis et al., 2015), we also wanted to examine continuing changes in the three frequency bands between ages 8- and 12-years. Se

• We examined three key questions First is

  2018-11-01

  

  We examined three key questions. First, is daily concordance in sleep time between parents and their adolescent child associated with neural concordance in DMN connectivity? Although prior research has investigated dyadic concordance in sleep behavior between parents and their child focusing on subj

• Additionally our data raise the possibility that extreme gro

  2018-11-01

  

  Additionally, our data raise the possibility that extreme group differences in aerobic fitness (e.g., 70th percentile versus 30th percentile VO2max) may be needed to demonstrate hippocampal volume effects (Chaddock et al., 2010a), whereas CBF differences may be a more sensitive marker to understand

• br Acknowledgements br Specification Table br Value

  2018-11-01

  

  Acknowledgements Specification Table Value of the data Data The data for this study has been analysed to a certain extent, archived and updated at each draw in [1]. This data article contains data generated from different approach other than what was contained in [1] and it is publicly a

• The genotype and allele frequencies of the

  2018-11-01

  

  The genotype and allele frequencies of the DFEB1 −20G>A (rs11362), −44C>G (rs1800972), and −52G>A (rs1799946) polymorphisms in psoriasis patients and controls are presented in Table 2. Some of the study participants could not be genotyped for the polymorphisms because their DNA samples had been used

• La subordinaci n adaptada no emerge de forma

  2018-11-01

  

  La subordinación adaptada no emerge de forma azarosa; su proceso de construcción y apropiación en las mujeres está fuertemente determinada por las representaciones que sustentan la misma cultura, regulada por un sistema de dominación masculina. La antropóloga Michelle Zimbalist (1979) efectuó estudi

• Alumno Negro Yo considero que hay mucha

  2018-11-01

  

  Alumno Negro: Yo considero que hay mucha presión social siempre en estos temas, ¿no? Lo que vemos aquí tal vez es una perspectiva de una rendición de cuentas por parte de las mujeres hacia la sociedad. En cuanto surgen temas tan polémicos como el aborto, la eutanasia, matrimonios homosexuales, etc.,

• Increased understanding of tumor immunology leads

  2018-10-31

  

  Increased understanding of tumor immunology leads to the development of effective targeted therapies. The molecular diagnostic of cancer is also rapidly developed recently. More and more targeted therapeutic agents across various cancer subtypes have been approved by the US Food and Drug Administrat

• br Review of related literature br Study area Akure

  2018-10-31

  

  Review of related literature Study area Akure is the capital city of Ondo State in southwest Nigeria. It is a medium-sized city with a imidazoline receptors of 360,268 according to the 2006 National Population and Housing Census (Federal Republic of Nigeria, FRN, 2009). With a 3% yearly incre

• br Conclusions and future directions The

  2018-10-31

  

  Conclusions and future directions The toxic effects of Aβ1–42 on hippocampal neurons in culture were reversed by d-β-hydroxybutyrate, suggesting that ketone bodies may have neuroprotective efficacy [53]. Some animal studies have shown that high-fat diets are associated with elevated Aβ loads [78,

• In following a rise in the

  2018-10-31

  

  In 2013, following a rise in the number of providers of autologous-based stem cell treatments, the ISSCR released an additional statement reiterating the criteria under which stem cell research should be translated – even when the pituitary adenylate cyclase-activating peptide are from the patient

• In the present study we

  2018-10-31

  

  In the present study, we tested five different pharmacological agents that are commonly used as selective inhibitors of Nodal/Activin signaling, namely SB431542, LY364947, A-83-01, SB505124, and SB525334 (Inman et al., 2002; Callahan et al., 2002; Laping et al., 2002; DaCosta Byfield et al., 2004; L

• br Materials and methods br Results

  2018-10-31

  

  Materials and methods Results Discussion Our results show the potential of H2A.Z to provide a highly specific biomarker for identifying leukotriene receptor antagonists in tissues that are undergoing two tightly linked processes, deterministic asymmetric self-renewal and non-random segrega

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