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Our systematic review demonstrated that the majority
2018-11-07

Our systematic review demonstrated that the majority of NOD2-smoking studies were underpowered to detect an interaction; for example, 10 identified studies included fewer than 300 participants (de Diego et al., 2006; Giachino et al., 2004; Laghi et al., 2005; Mardini et al., 2005; Mendoza et al., 20
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Recently several supervised learning methods such as decisio
2018-11-07

Recently, several supervised learning methods, such as decision trees, have been applied to the analysis of cDNA microarrays to refine prognosis in nasopharyngeal carcinoma, breast cancer and non–small-cell lung cancer.(Chen et al., 2007) State-of-the-art classification algorithms such as support ve
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For each of the rHSA samples approximately g
2018-11-07

For each of the rHSA samples, approximately 10µg were diluted in 50mM ammonium bicarbonate to a total volume of 200µl. To each solution 10µl of 250mM dithiothreitol (DTT) in 50mM NH4HCO3 were added followed by incubation for 1h at 60°C. Next, 20µl of 250mM iodoacetamide in 50mM NH4HCO3 were added a
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br Acknowledgments We thank Richard A Flavell Yale Universit
2018-11-07

Acknowledgments We thank Richard A. Flavell, Yale University, and Roger J. Davis, University of Massachusetts Medical School, for their kind gift of the MKK3-deficient mice. We also thank Mary LoPresti and Jean Kanyo (Yale MS & Proteomics Resource) for their assistance with sample preparation and
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br Experimental design materials and methods The preparation
2018-11-07

Experimental design, materials, and methods The preparation of recombinant protein and crystallization for the periaxin PDZ (post-synaptic density-95, discs large, zona occludens-1)-like domain and the gliomedin olfactomedin (OLF) domain have been described [4,5]. Crystals of the periaxin PDZ-lik
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It should be noted that our analyses were conducted
2018-11-07

It should be noted that our analyses were conducted in a between-subjects fashion. Previous work with adults has suggested that within- and between-subjects estimates of coupling reflect similar constructs (Schutter and Knyazev, 2012). However, this work also presents the possibility that coupling m
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We argue here that memory is far
2018-11-07

We argue here that memory is far from unitary. Improvements in the precision of lesion studies (e.g., Heuer and Bachevalier, 2011; Pascalis et al., 2009) and imaging in human adults (e.g., Bakker et al., 2008; Ranganath, 2010; Staresina et al., 2011) demonstrate that MTL supports diverse forms of me
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br Study chasing versus inanimate motion br Study chasing ve
2018-11-07

Study 1: chasing versus inanimate motion Study 2: chasing versus random General discussion Both studies postulate evidence of a strong positive amplitude for the chasing agent in the low occipital and post temporal areas 400ms post PF-2341066 onset. Given that prior research examining early
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Our longitudinal data suggest an increased
2018-11-07

Our longitudinal data suggest an increased caudate nucleus volume in the ASD and DD groups, including 2–3-year-old and 4–5-year-old children. In the ASD group, we found a 16.8% increase in left caudate volume over a 2-year interval compared with 12.8% and 17.5% increase in right caudate volume. The
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br What is the causal relation between affect biased
2018-11-07

What is the causal relation between affect-biased attention and socioemotional functioning? Statements such as “attentional bias towards threat is implicated in the development, and maintenance of anxiety” are not uncommon in the literature. Indeed, we have made the same statement in the current
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Outline Interoception is described as
2018-11-07

Outline Interoception is described as the perception of the internal state of one’s body; as such, signals including those relating to hunger, temperature, heart rate, and blood sugar levels are all interoceptive in nature. These bodily signals are thought to be represented within the insula and an
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So how exactly are growth mindsets
2018-11-07

So how exactly are growth mindsets linked with resilience to setbacks? Research has primarily focused on the associations between mindsets and motivational variables such as attributions and achievement goals to address this question (Dweck et al., 1995; Dweck and Leggett, 1988; Hong et al., 1999;
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The question of how such atypicalities can
2018-11-07

The question of how such atypicalities can result in an uneven cognitive profile in which some skills can be near (or even better than) typical, while others show deficits has always posed a significant challenge to accounts of developmental disorders that postulate general factors, such as widespre
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THz Biomed or THz radiation is proposed an efficient label
2018-11-06

THz-Biomed, or THz radiation, is proposed an efficient, label-free, reagent-less and nondestructive detection methods, which is indispensable for laboratory medicine. Studies show that low-frequency internal motions (e.g., skeleton vibration and rotation) and weak bonds (e.g., Hydrogen bond and van
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Several studies have shown that LVI is a strong
2018-11-06

Several studies have shown that LVI is a strong stage-independent prognostic factor. The presence of LVI is associated with an increased risk of regional LN metastasis. Lim et al also revealed that LVI is an independent factor for unfavorable prognosis. In our present study, however, no significant
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