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Finally it is possible that
2020-04-21
Finally, it is possible that also species differences (rat primary preadipocytes vs mouse 3T3-L1 cells) could contribute to these discrepancies. A recent study suggested that 3T3-L1 5 03 may contain adipocyte precursors with multiple cell lineage characteristics which may contribute to different bi
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We next turned our attention to the position
2020-04-21
We next turned our attention to the 6-position of the indole (). It was found that the chlorine atom present in was extremely important. The des-chloro analogue showed nearly 30-fold less affinity for the EP receptor in the binding assay and was nearly 30-fold lower in activity in the functional ass
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Using HPLC and an amino acid
2020-04-21
Using HPLC and an amino CAY10499 sequencer, the site of cleavage into the fluorogenic substrate AbzFRQEDDnp, determined as specific to the endopeptidase STH2, was analyzed and identified as being R2-Q3, and into substrate AbzFGQEDDnp, determined as specific to SH1, it was G2-Q3 (Fig. 5, Fig. 6). T
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Given that CE plays an essential role in schistosome
2020-04-21
Given that CE plays an essential role in schistosome invasion, its immunoreactivity and protective potential is of significant interest. The native form of SmCE was found to be poorly immunogenic in immunized mice. An earlier study found that sera from S. mansoni patients have shown the presence of
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br Materials and methods br Results
2020-04-20
Materials and methods Results Discussion In particular, we showed that pancreatic neuroendocrine tumor 1-NM-PP1 sale recognize cAMP as a stimulatory signal for cell proliferation. Conversely, cAMP was found to have an inhibitory effect on cell proliferation in bronchial carcinoids cells. Th
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On the opposite side sPLA X has also
2020-04-20
On the opposite side, sPLA2-X has also been implicated in the pathology of cancer [167,168]. Human sPLA2-X induces lipid droplet formation in Ras-driven MDA-MB-231 triple-negative breast cancer Conessine and promotes their survival during nutrient stress. It acts through the products of its enzymat
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The possibility of harm with
2020-04-20
The possibility of harm with DPP-4 inhibitors in patients with clinically overt heart failure has been recently highlighted by the results of the VIVIDD (Vildagliptin in Ventricular Dysfunction Diabetes) trial (68), the only trial to date that has been designed to evaluate the effects of a DPP-4 inh
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br Introduction In most of the
2020-04-20
Introduction In most of the angiosperms, sexual reproduction requires a process called double fertilization where the specialized cell division called meiosis produces haploid gametes combine to form diploid (2n) embryo. In (-)-Huperzine A receptor to this, apomixis, naturally occurs in at least
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The co occurrence of the AA and the AA
2020-04-20
The co-occurrence of the AA12 and the AA8 domains in CcPDH would allow for electron transfer between these domains. Such electron transfer is known to occur in CDH, and the AA8 family in CAZy is in fact largely comprised of cytochrome domains of multi-domain CDHs. One notable exception concerns the
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Arsenic could cause apoptosis in both benign and malignant
2020-04-20
Arsenic could cause apoptosis in both benign and malignant cells (Akao et al., 2000, Gupta et al., 2003, Namgung and Xia, 2001). However, at present, little is known about the consequences of arsenic-treated urothelial cells in autophagy and expression of its related proteins. In addition, the alter
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In order to further understand the biological significance o
2020-04-20
In order to further understand the biological significance of cell-collagen X interactions, we have examined the possibilities of involvement of other collagen receptors in cell binding to collagen X. The present study demonstrates that collagen X is a ligand for DDR2. DDR2 has been observed to bind
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We propose the following model for how
2020-04-20
We propose the following model for how B cell-guiding EBI2 ligand gradients are established in lymphoid tissues. CH25H and CYP7B1 are needed in radiation-resistant stromal cells, are abundantly expressed and active in CXCL13+ and CCL21+ FRCs, but not lymphocytes, and are poorly expressed in the inne
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Characterization factor is another variable suggested in the
2020-04-20
Characterization factor is another variable suggested in the presented correlation. Specific gravity (SG) and normal boiling point of hydrocarbons are needed to calculate Watson characterization factor [61], [62]: The boiling point of bitumen cannot be precisely measured, because bitumens contain e
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Protionamide br Materials and methods br Results br Discussi
2020-04-17
Materials and methods Results Discussion Regardless of obvious beneficial effects of GC on acceleration of foetal lung and cardiomyocytes maturation (Kamath-Rayne et al., 2012; Rog-Zielinska et al., 2015), the current study revealed that GC exposure during late pregnancy induces IR and alte
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Characterization factor is another variable suggested in the
2020-04-17
Characterization factor is another variable suggested in the presented correlation. Specific gravity (SG) and normal boiling point of hydrocarbons are needed to calculate Watson characterization factor [61], [62]: The boiling point of bitumen cannot be precisely measured, because bitumens contain
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